MCQ on RNA Interference with Answers (PDF)

RNA interference (RNAi) is a natural biological process where small RNA molecules inhibit gene expression by degrading or blocking the translation of specific messenger RNA (mRNA). It helps regulate gene activity and defends against viral infections in cells. The process involves two main types of small RNA: small interfering RNA (siRNA) and microRNA (miRNA). Both bind to complementary sequences on target mRNA, leading to its degradation or silencing, preventing protein production. RNAi is a powerful tool in research and medicine for silencing genes to study their functions and for developing therapies for diseases like cancer and viral infections. This is an MCQ on RNA Interference with Answers. You can Download the questions as PDF from the results window of this quiz.

Molecular Biology Notes  |  Molecular Biology PPTs  |  Molecular Biology MCQs

1. 
What is the primary function of RNA interference (RNAi)?

2. 
Which molecule is central to the RNAi process?

3. 
Which enzyme is responsible for processing long double-stranded RNA (dsRNA) into siRNA in RNA interference?

4. 
The RNA-induced silencing complex (RISC) is responsible for which function in RNAi?

5. 
What type of RNA is typically produced during the process of RNAi to silence gene expression?

6. 
What is the primary role of microRNAs (miRNAs) in RNA interference?

7. 
Which of the following organisms were used in the discovery of RNA interference?

8. 
In the RNAi pathway, what is the role of Argonaute proteins?

9. 
Which of the following describes the mechanism of action of RNAi?

10. 
What is the primary difference between siRNAs and miRNAs?

11. 
Which of the following is a key therapeutic application of RNA interference?

12. 
In which phase of gene expression does RNA interference function?

13. 
Which of the following is a common delivery system for siRNA in therapeutic RNA interference?

14. 
In plants, RNA interference plays an important role in which of the following processes?

15. 
What is the outcome of RNA interference in eukaryotic cells?

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