MCQ on Extrinsic Pathway of Apoptosis (Receptor Mediated Programmed Cell Death)

The extrinsic pathway of apoptosis is an external stimuli induced signaling mechanism that initiates programmed cell death. It involves the binding of death ligands, such as tumor necrosis factor (TNF) or Fas ligand, to death receptors on the cell surface. This binding activates caspase enzymes, leading to the activation of downstream apoptotic processes, including DNA fragmentation and cell dismantling. This MCQ on Extrinsic Pathway of Apoptosis (Programmed Cell Death) will help you to study the molecular mechanism of receptor mediated programmed cell death pathway in the cells.

Notes on  Apoptosis Intrisic Pathway of Apoptosis  |  Extrinsic Pathway of Apoptosis  |

MCQ on Apoptosis  | Intrinsic Pathway of Apoptosis  |




Welcome to your MCQ on Extrinsic Pathway of Apoptosis

Binding of ligands to death receptors leads to the formation of a:

Death receptors belong to which family of proteins?

Which protein is recruited to the DISC and initiates downstream signaling in the extrinsic pathway?

Which death receptor is most commonly associated with the extrinsic pathway?

Activation of death receptors triggers the activation of which caspase?

Defects in the extrinsic pathway can lead to:

The activated caspase-8 in the extrinsic pathway directly activates:

The extrinsic pathway of apoptosis converges with the intrinsic pathway at the level of:

The extrinsic pathway of apoptosis is often associated with:

The extrinsic pathway of apoptosis can be triggered by which of the following stimuli?

Which of the following is a ligand for the Fas death receptor?

The extrinsic pathway of apoptosis is initiated by:

The extrinsic pathway of apoptosis is primarily regulated by:

Which of the following is NOT a death receptor associated with the extrinsic pathway?

Which of the following is NOT a mechanism by which cells can escape the extrinsic pathway of apoptosis?




 

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