MCQ on Post Transcriptional Modification

Post-transcriptional modification refers to alterations made to mRNA molecules after transcription but before translation in eukaryotic cells. These modifications include 5′ capping, 3′ polyadenylation, and splicing, which enhance stability, regulate translation, and increase mRNA diversity, essential for proper gene expression. This is an MCQ on Post Transcriptional Modification with answer key.

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1. 
Post-transcriptional modifications primarily occur in which type of nucleic acid?

2. 
Which of the following post-transcriptional modifications involves the addition of a protective 5' cap to mRNA?

3. 
The 5' cap added to mRNA serves multiple purposes, including:

4. 
Which post-transcriptional modification involves the addition of a poly-A tail to the 3' end of mRNA?

5. 
The poly-A tail added to mRNA is essential for:

6. 
In eukaryotes, the removal of introns and joining of exons in pre-mRNA is a crucial post-transcriptional modification called:

7. 
The spliceosome is a complex of RNA and protein that carries out:

8. 
Alternative splicing allows for the production of multiple protein isoforms from a single gene. What is the primary mechanism behind alternative splicing?

9. 
The presence of a 3' untranslated region (UTR) in mature mRNA molecules can:

10. 
Which post-transcriptional modification involves the removal of specific nucleotides from the 3' end of tRNA molecules?

11. 
The addition of specific chemical groups, such as methyl groups, to RNA molecules is a post-transcriptional modification known as:

12. 
The removal of the 5' cap or the poly-A tail from mRNA can lead to:

13. 
In the process of RNA editing, specific nucleotides within an mRNA molecule can be altered. Which nucleotide is commonly modified in RNA editing?

14. 
RNA interference (RNAi) is a post-transcriptional regulatory mechanism that involves the:

15. 
Post-transcriptional modifications are crucial for regulating gene expression and generating protein diversity. Which step of gene expression primarily involves these modifications?

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MCQ on Post Transcriptional Modification




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