What is Nucleotide Excision Repair (NER)? As the name suggests it is a type of DNA repair mechanism. In nucleotide excision repair or NER, the damaged base along with a short stretch of healthy strand is removed and later the gap is refilled with correct nucleotides. Thus the NER pathway operates by ‘cut and patch’ mechanism. Even though nucleotide excision […]
Continue ReadingCSIR NET Life Sciences Question paper June 2015 with Answer Key and Explanations Part II (Part B Question 41 – 55)
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (CSIR) & UGC (Original Question Paper) PART: B (Questions 41 – 55) 41. Which of the following statements about LEAFY (LFY), a regulatory gene in Arabidopsis thaliana, is correct? a. LEAFY (LFY) is involved in floral meristem identity b. LEAFY (LFY) is involved in leaf expansion c. LEAFY (LFY) is involved in […]
Continue ReadingCSIR NET Life Sciences Question Paper: June 2015: with Answer Key and Explanations: Part I
CSIR/JRF/NET: Life Sciences, June 2015 (I) COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (CSIR) & UGC PART: B (Questions 21 – 40) (21). A 1% (w/v) solution of a sugar polymer is digested by an enzyme (20ug, MW = 200,000). The rate of monomer sugar (MW = 400) liberated was determined to have a maximal initial velocity of 100 mg formed/ […]
Continue ReadingDNA Repair: Part III – Base Excision Repair (BER) Mechanism
Cancer is a disease of the genome. And that’s what happens. You make mistakes in a cell somewhere in your body that causes it to start to grow when it should’ve stopped, and that’s cancer. And those mistakes are mistakes of DNA. Francis Collins What is Base Excision Repair or BER? As the name suggests, it is a type of DNA […]
Continue ReadingPhotoreactivation : Method of DNA Repair for the Recovery of UV Induced DNA Damages by Phytolyase Enzyme and Visible Light
Science is beautiful when it makes simple explanations of phenomena or connections between different observations. Stephen W. Hawking, 2011 What is Photoreactivation? Photoreactivation is a type of DNA repair mechanism present in prokaryotes, archaea and in many eukaryotes. It is the recovery of ultraviolet irradiated damages of DNA by visible light. As the name suggests, it is a light dependent […]
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