DNA Repair BER Overview

DNA Repair: Part III – Base Excision Repair (BER) Mechanism

Cancer is a disease of the genome. And that’s what happens. You make mistakes in a cell somewhere in your body that causes it to start to grow when it should’ve stopped, and that’s cancer. And those mistakes are mistakes of DNA. Francis Collins What is Base Excision Repair or BER? As the name suggests, it is a type of DNA […]

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Photolyase Mechanism of Action

Photoreactivation : Method of DNA Repair for the Recovery of UV Induced DNA Damages by Phytolyase Enzyme and Visible Light

Science is beautiful when it makes simple explanations of phenomena or connections between different observations. Stephen W. Hawking, 2011 What is Photoreactivation? Photoreactivation is a type of DNA repair mechanism present in prokaryotes, archaea and in many eukaryotes. It is the recovery of ultraviolet irradiated damages of DNA by visible light. As the name suggests, it is a light dependent […]

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DNA Repair Mechanism

DNA Repair Mechanism – Part I Introduction (DNA Damaging Agents, DNA Damages and Recovery of DNA Damages)

“Genetic variation is important for evolution, but the survival of the individuals demand genetic stability” DNA is the genetic information carrier molecule in the cell and thus it is very essential to keep the genetic information intact. Even though DNA holds a prime position, it is one of the highly susceptible molecules in the cells because DNA can be damaged […]

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Lecture notes in Microbiology

Difference between Prokaryotic & Eukaryotic Transcription

Prokaryotic vs Eukaryotic Transcription Prokaryotic Vs Eukaryotic Transcription: Transcription is a process by which the genetic information present in the DNA is copied to an intermediate molecule (RNA). The sequence in the RNA is complementary to that of the gene which is transcribed and thus the RNA retains the same information as the gene itself. Transcription is a universal process […]

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Difference Between Prokaryotes and Eukaryotes

Prokaryotes Vs Eukaryotes: (Similarities and Differences Between Prokaryotes & Eukaryotes)

Difference Between Prokaryotes and Eukaryotes: Prokaryotes and Eukaryotes are the two fundamental or basic classes of cells. They are mainly distinguished by their size and internal structures. The existence of two classes of cells without any intermediate type represents one of the most fundamental evolutionary separations in the living world. Prokaryotes are structurally and evolutionarily more primitive to eukaryotes. Even […]

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