Extrinsic Pathway of Apoptosis (The Receptor-Mediated Programmed Cell Death Pathway) In the extrinsic pathway of apoptosis, the death-inducing signal for the programmed cell death is triggered by an external stimulus. For receiving such an external death-inducing signal, the cell possesses plasma membrane receptors specific to each stimulus and thus the extrinsic signalling of apoptosis is also known as the Receptor […]
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Intrinsic Pathway of Apoptosis (Apoptosis Molecular Mechanism Part 1)
Two Types of Apoptosis In the previous post, we have discussed the characteristic features and significance of programmed cell death or apoptosis. As we discussed, the stimuli for the execution of programmed cell death can be of internal or external to the apoptotic cell. Based on the source of stimuli, there are two types of apoptosis signaling pathways operate in […]
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