MCQ on Pyrimidine: Structure, Biosynthesis and Functions







Pyrimidines are nitrogenous organic compounds with a single-ring structure. They are fundamental building blocks in DNA and RNA, with cytosine, thymine (found in DNA), and uracil (found in RNA) as common examples. Pyrimidines participate in genetic coding and other cellular processes. This is an MCQ on Pyrimidine Structure and Functions.

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1. 
What class of organic compounds do pyrimidines belong to?

2. 
Pyrimidines are heterocyclic compounds. How many carbon atoms are present in the pyrimidine ring?

3. 
In RNA, which base pairs with cytosine?

4. 
Which of the following is a pyrimidine-containing nucleotide?

5. 
What type of bond connects the pyrimidine and purine base pairs in DNA and RNA?

6. 
Which genetic disorder is characterized by the inability to properly metabolize uracil, leading to a buildup of toxic substances?

7. 
What is the primary function of the enzyme thymidylate synthase in pyrimidine metabolism?

8. 
Which of the following is not a pyrimidine base found in nucleic acids?

9. 
Which pyrimidine base is specific to DNA and not found in RNA?

10. 
In pyrimidine metabolism, which enzyme catalyzes the conversion of orotate to UMP (uridine monophosphate)?

11. 
Pyrimidines are essential components of which biological molecules?

12. 
What is the primary function of the enzyme dihydroorotate dehydrogenase in pyrimidine metabolism?

13. 
In pyrimidine metabolism, which enzyme is responsible for the conversion of CTP to dCTP, an essential precursor for DNA synthesis?

14. 
Which pyrimidine base can pair with adenine through hydrogen bonding in DNA?

15. 
Which two nitrogenous bases in DNA are pyrimidines?

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