MCQ on Proteoglycans

Proteoglycans are macromolecules composed of a core protein linked to long chains of glycosaminoglycans (GAGs). Abundant in extracellular matrices, they provide structural support, regulate cell behavior, and contribute to tissue resilience. The negatively charged GAGs confer unique properties to proteoglycans, influencing their biological functions. This is an MCQ on Proteoglycans Structure and Functions.

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1. 
What are proteoglycans?

2. 
What is the primary function of proteoglycans in the extracellular matrix (ECM) of tissues?

3. 
Proteoglycans consist of a core protein and long chains of:

4. 
Which type of glycosaminoglycan (GAG) is commonly found in proteoglycans and contributes to their gel-like properties?

5. 
In the structure of proteoglycans, GAG chains are covalently attached to the core protein through:

6. 
Which of the following functions is typically associated with proteoglycans in cartilage and connective tissues?

7. 
Which proteoglycan is a major component of cartilage and is responsible for its resilience and shock-absorbing properties?

8. 
What is the role of proteoglycans in the skin, contributing to its elasticity and hydration?

9. 
In addition to their structural roles, proteoglycans are involved in cell signaling and adhesion by interacting with molecules such as growth factors. What is the name of the region of a proteoglycan that binds to these molecules?

10. 
What role do proteoglycans play in the eye's vitreous humor, a gel-like substance that helps maintain the eye's shape?

11. 
Which of the following is a function of proteoglycans in the brain and nervous system?

12. 
The glycosaminoglycan (GAG) keratan sulfate is commonly found in proteoglycans of the:

13. 
Proteoglycans have a high negative charge due to the sulfate and carboxyl groups on their GAG chains. What is the significance of this negative charge in the ECM?

14. 
Which proteoglycan is found in the synovial fluid of joints and contributes to joint lubrication and shock absorption?

15. 
In the context of proteoglycans, what is the significance of the "aggrecan" name for a specific type of proteoglycan?

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mcq on proteoglycans

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